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Mpox resurgence
9 October 2024 @ 13.00 CET This webinar will focus on the virology, ecology, and transmission dynamics of the ...
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AMR in low resource settings and / or displaced populations 22 October 2024 @ 17.00 (CET)
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On demand recording coming soon.Join us for an insightful webinar titled "Optimising Paediatric Antibiotic Therapy: A Model-Informed Precision Dosing ...
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ISAC organised an MRSA and Infection Control symposium at the 19th International Symposium on Staphylococci and Staphylococcal Infections (ISSSI) in ...
Watch nowABX Guide: Africa region
The next webinar in the series to launch the ABX Guide, an open-access antibiotic treatment-guide focussed on pathogen-directed treatment for ...
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The deadline to register at a reduced rate to attend the 33rd International Congress of Antimicrobial Chemotherapy (ICC) in Istanbul, ...
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Organised by the ISAC MRSA Working Group. Watch this webinar which had over 500 registrants from 100 countries.
Watch webinarOptimising paediatric antibiotic ...
On demand recording coming soon.Join us for an insightful webinar titled "Optimising Paediatric Antibiotic Therapy: A Model-Informed Precision Dosing ...
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ISAC Working Group Articles
The following are a list of publications written under the auspices of ISAC:
Alliance for the Prudent Use of Antibiotics (APUA)
The battle against fungi: lessons in antifungal stewradship from COVID 19 times
Souha S Kanj, Sara F Haddad, Jacques F Meis, Paul E Verweij, Andreas Voss, Riina Rautemaa-Richardson, Gabriel Levy-Hara, Anuradha Chowdhary, Abdul Ghafur, Roger Brüggemann, Abhijit M Bal, Jeroen Schouten
Int J Antimicrob Agents. 2023 May 13;62(1):106846.
Diagnostic stewardship in infectious diseases: a continuum of antimicrobial stewardship in the fight against antimicrobial resistance
Johnny Zakhour, Sara F Haddad, Anthony Kerbage, Heiman Wertheim, Pierre Tattevin, Andreas Voss, Serhat Ünal, Abdoul Salam Ouedraogo, Souha S Kanj; International Society of Antimicrobial Chemotherapy (ISAC) and the Alliance for the Prudent Use of Antibiotics (APUA)
Int J Antimicrob Agents. 2023 Apr 13;62(1):106816.
Antimicrobial stewardship in the ICU in COVID-19 times: the known unknowns
Schouten J, De Waele, J, Lanckohr C et al, on behalf of the Alliance for the Prudent Use of Antibiotics (APUA).
Int J Antimicrob Agents. 2021 Oct;58(4):106409
Advocacy for Increased International Efforts for Antimicrobial Stewardship Actions in Low-and Middle-Income Countries on Behalf of Alliance for the Prudent Use of Antimicrobials (APUA), Under the Auspices of the International Society of Antimicrobial Chemotherapy (ISAC)
Tattevin P, Levy Hara G, Toumi A et al behalf of Alliance for the Prudent Use of Antimicrobials (APUA) under the auspices of the International Society of Antimicrobial Chemotherapy (ISAC)
Front Med (Lausanne). 2020 Aug 25;7:503.
Perceived Challenges of COVID-19 Infection Prevention and Control Preparedness: A Multinational Survey
Tartari E, Hopman J, Allegranzi B et al on behalf of International Society of Antimicrobial Chemotherapy Infection and Prevention Control ISAC-IPC Working Group
J Glob Antimicrob Resist. 2020 Sep;22:779-781.
Antimicrobial Resistance
MDRO Beijing Consensus Meeting Report: Global burden of multidrug-resistant organisms' current antimicrobial resistance problems in Asia-Pacific.
Gould IM, Wang GQ, Wu JJ et al.
J Glob Antimicrob Resist. 2014 Mar;2:7-9
Antimicrobial Stewardship (now APUA)
New Drugs for Multidrug-Resistant Gram-Negative Organisms: Time for Stewardship.
Jean SS, Gould IM, Lee WS et al.
Drugs. 2019 May;79:705-714
Ten key points for the appropriate use of antibiotics in hospitalised patients: a consensus from the Antimicrobial Stewardship and Resistance Working Groups of the International Society of Chemotherapy.
Levy Hara G, Kanj SS, Pagani L et al.
Int J Antimicrob Agents. 2016 Sep;48:239-46
"Ten Commandments" for the Appropriate use of Antibiotics by the Practicing Physician in an Outpatient Setting.
Levy-Hara G, Amábile-Cuevas CF, Gould I et al.
Front Microbiol. 2011 Nov 24;2:230
Bone, Skin & Soft Tissue Infections
Hot topics in Diabetic Foot Infections
Saeed K, Esposito S, Akram, A on behalf of the International Society of Antimicrobial Chemotherapy
Int J Antimicrob Agents. 2020 Jun;55(6):105942
Hot topics on procalcitonin use in clinical practice, can it help antibiotic stewardship?
Saeed K, del Castillo JG, Backous C et al on behalf of ISAC.
Int J Antimicrob Agents. 2019;54:686-696.
Hot Topics on Vertebral Osteomyelitis from the International Society of Antimicrobial Chemotherapy.
Saeed K, Esposito S, Ascione T et al on behalf of ISAC.
Int J Antimicrob Agents. 2019 June;54:125-133
An update on Staphylococcus aureus infective endocarditis from the International Society of Antimicrobial Chemotherapy (ISAC).
Saeed K, Bal AM, Gould IM et al.
Int J Antimicrob Agents. 2019 Jan;53:9-15
Hot topics in necrotising skin and soft tissue infections
Saeed K, Esposito S, Gould I et al on behalf of ISAC.
Int J Antimicrob Agents. 2018 Jul;52:1-10
Panton-Valentine leukocidin-positive Staphylococcus aureus: a position statement from the International Society of Chemotherapy.
Saeed K, Gould I, Esposito S et al on behalf of ISAC.
Int J Antimicrob Agents. 2018 Jan;51:16-25
Prosthetic joints: shining lights on challenging blind spots.
Saeed K, Dryden M, Bassetti M et al on behalf of ISAC.
Int J Antimicrob Agents. 2017 Feb;49:153-161
Hot topics in the diagnosis and management of skin and soft-tissue infections.
Esposito S, Bassetti M, Bonnet E et al.
Int J Antimicrob Agents. 2016 Jul;48:19-26
Diagnosis and management of skin and soft-tissue infections (SSTI): a literature review and consensus statement on behalf of the Italian Society of Infectious Diseases and International Society of Chemotherapy.
Esposito S, Bassetti M, Borre S et al.
J Chemother. 2011 Oct;23:251-62
ISAC
ISAC: the way forward
Andreas Voss (ISAC President) and Geoff Coombs (ISAC President Elect) set out ISAC's strategy for the next three years.
History of the International Society of Antimicrobial Chemotherapy
This article by Professor Alasdair Geddes was published in both ISAC's journals - the International Journal of Antimicrobial Agents (IJAA) and Journal of Global Antimicrobial Resistance (JGAR) - to celebrate the 60th anniversary of ISAC.
Infection Prevention & Control
Not sick enough to worry? "Influenza-like" symptoms and work-related behavior among healthcare workers and other professionals: Results of a global survey.
Tartari E, Saris K, Kenters N et al on behalf of the ISAC IPC Working Group.
PLoS One. 2020 May 13;15(5):e0232168.
Influenza_Poster.pdf
Not sick enough to worry? "Flu-like" symptoms and work-related behaviour among healthcare workers and other professionals worldwide.
Ermira Tartari, Katja Saris, Nikki Kenters, Kalisvar Marimuthu, Andreas Widmer, Peter Collignon, Vincent Cheng, Shuk Ching Wong, Tom Gottlieb, Eli Perencevich, Paul Tambyah, Benedetta Allegranzi, Angela Dramowski, Michael Edmond, Members of the ISAC-IPC working group, Andreas Voss On behalf of: ISAC, Infection Prevention and Control (IPC) Working Group
Control of Candida auris in healthcare institutions: outcome of an ISAC expert meeting
Kenters N, Kiernan M, Chowdhary A et al on behalf of ISAC.
Int J Antimicrob Agents. 2019 Oct;54:400-406
Infections in the ICU & Sepsis
Antimicrobial therapeutic drug monitoring in critically ill adult patients: a Position Paper.
Abdul-Aziz MH, Alffenaar JC, Bassetti M et al on behalf of Infection Section of European Society of Intensive Care Medicine (ESICM); Pharmacokinetic/pharmacodynamic and Critically Ill Patient Study Groups of European Society of Clinical Microbiology and Infectious Diseases (ESCMID); Infectious Diseases Group of International Association of Therapeutic Drug Monitoring and Clinical Toxicology (IATDMCT); Infections in the ICU and Sepsis Working Group of International Society of Antimicrobial Chemotherapy (ISAC).
Intensive Care Med. 2020 Jun;46(6):1127-1153.
MRSA
Future trends in the treatment of methicillin-resistant Staphylococcus aureus (MRSA) infection: An in-depth review of newer antibiotics active against an enduring pathogen.
Bal AM, David MZ, Garau J et al.
J Glob Antimicrob Resist. 2017 Sep;10:295-303
Methicillin-resistant Staphylococcus aureus infections: A review of the currently available treatment options.
Purrello SM, Garau J, Giamarellos E et al.
J Glob Antimicrob Resist. 2016 Dec;7:178-186
Genomic insights into the emergence and spread of international clones of healthcare-, community- and livestock-associated meticillin-resistant Staphylococcus aureus: Blurring of the traditional definitions.
Bal AM, Coombs GW, Holden MTG et al.
J Glob Antimicrob Resist. 2016 Sep;6:95-101
Preventing the introduction of meticillin-resistant Staphylococcus aureus into hospitals.
Larsen J, David MZ, Vos MC et al.
J Glob Antimicrob Resist. 2014 Dec;2:260-268
Treatment options for methicillin-resistant Staphylococcus aureus (MRSA) infection: Where are we now?
Edwards B, Andini R, Esposito S et al.
J Glob Antimicrob Resist. 2014 Sep;2:133-140
Meticillin-resistant Staphylococcus aureus (MRSA) update: New insights into bacterial adaptation and therapeutic targets.
Purrello SM, Daum RS, Edwards GF et al.
J Glob Antimicrob Resist. 2014 Jun;2:61-69
Vancomycin in the treatment of meticillin-resistant Staphylococcus aureus (MRSA) infection: End of an era?
Bal AM, Garau J, Gould IM et al.
J Glob Antimicrob Resist. 2013 Mar;1:23-30
New insights into meticillin-resistant Staphylococcus aureus (MRSA) pathogenesis, treatment and resistance.
Gould IM, David MZ, Esposito S et al.
Int J Antimicrob Agents. 2012 Feb;39:96-104
Meticillin-resistant Staphylococcus aureus (MRSA): global epidemiology and harmonisation of typing methods.
Stefani S, Chung DR, Lindsay JA et al.
Int J Antimicrob Agents. 2012 Apr;39:273-82
Update on the prevention and control of community-acquired meticillin-resistant Staphylococcus aureus (CA-MRSA).
Skov R, Christiansen K, Dancer SJ et al.
Int J Antimicrob Agents. 2012 Mar;39:193-200
Meticillin-resistant Staphylococcus aureus (MRSA): screening and decolonisation.
Cookson B, Bonten MJ, Mackenzie FM et al.
Int J Antimicrob Agents. 2011 Mar;37:195-201
Management of serious meticillin-resistant Staphylococcus aureus infections: what are the limits?
Gould IM, Cauda R, Esposito S et al.
Int J Antimicrob Agents. 2011 Mar;37:202-9
Rapid Diagnostics & Biomarkers
How are rapid diagnostic tests for infectious diseases used in clinical practice: a global survey by the International Society of Antimicrobial Chemotherapy (ISAC)
Poole, S, Townsend J, Wertheim et al on behalf of the ISAC Rapid Diagnostic and Biomarkers Working Group
Eur J Clin Microbiol Infect Dis. 2021 Feb;40(2):429-434
Viral Infections
Grasping knowledge, attitude, and perception towards monkeypox among healthcare workers and medical students: an Egyptian cross-sectional study
Fatma Amer, Hanaa Nofal, Manar Gebriel et al
Frontiers. 2024 Feb.
Viral infections
Mpox: Risks and approaches to prevention
Amer F, Khalil HES, Elahmady M et al
J Infect Public Health. 2023 Jun;16:901-910
Growing shreds of evidence for monkeypox to be a sexually transmitted infection
Amer FA, Hamaad, NH, Wegdan A-A et al
Infez Med 2022 Sep;30(3) Ahead Jul 3
FIFA World Cup 2022 in Qatar: Mitigating the risk of imported infections amid the COVID-19 pandemic, monkeypox outbreak and other emerging diseases
Sah R, Alshahrani NZ, Shah P et al
Travel Medicine and Infectious Disease, Volume 50, 2022
A Potential Monkeypox Pandemic: Are We Making the Same Mistakes as COVID-19?
Sah R, Reda A, Abdelaa A et al
New Microbes and New Infections, https://doi.org/10.1016/j.nmni.2022.101030
Monkeypox virus infection in women and non-binary people: uncommon or neglected?
Alfonso J Rodriguez-Morales, Fatma A Amer
The Lancet. Vol. 400No. 10367Published: December 03, 2022
Assessment and outcome of hospitalized patients during delta variant COVID-19 pandemic: A multicenter international study
Fatma Abdelaziz Amer, Maysaa Abdallah Saeed et al
J Infect Dev Ctries. 2022 Nov 29;16(11):1715-1725
Zero by 2030 and OneHealth: The multidisciplinary challenges of rabies control and elimination
D. KatterineBonilla-Aldana, JulianRuiz-Saenz et al
Travel Med Infect Dis. 2023 Jan-Feb;51:102509.
RT- PCR testing of upper respiratory tract samples for diagnosis of SARS-CoV-2: Between justification and overestimation, a multi-center international study
Hammad NM, Saeed MA, ShaltoutSW et al
Travel Med Infect Dis. 2022 Apr 22;48:102334. doi: 10.1016/j.tmaid.2022.102334.
Individuals with covert severe acute respiratory syndrome coronavirus 2 infection: Are they a critical booby-trap?
Amer FA
Rev Soc Bras Med Trop. 2020; 53: e20200231.
Surveillance and impact of occult hepatitis B virus, SEN virus, and torque teno virus in Egyptian hemodialysis patients with chronic hepatitis C virus infection
Amer F, Yousif MM, Mohtady H, et al.
Int J Infect Dis. 2020;92:13-18
Immunological mechanisms controlling hepatitis C virus infection.
Amer FA.
Asian Pacific Journal of Tropical Disease. 2015: 5(2): 85-90
Immune-based strategies for treatment and prevention of hepatitis C virus infection.
Amer FA, Mansour MA, Mansour SA. The International Arabic Journal of Antimicrobial Agents. 2014: 1
Epidemiology of Hepatitis C Virus Infection in Egypt
Amer FA, Gohar M and Yousef M.
International Journal of Tropical Disease & Health. 2015: 7(3): 119-131.
