32nd ICC on-demand

Antibiotic allergy - a risk worth taking?

A/Prof. Jason Trubiano

Associate Prof. Jason Trubiano is the Director of the Department of Infectious Diseases, Austin Health and Head of the Drug and Antibiotic Allergy Service.

In this lecture, Dr Trubiano aims to address the following questions in relation to setting up an antibiotic allergy programme:

1. WHY should I address antibiotic allergy?
2. WHAT model of care should I employ for my setting?
3. HOW do I delabel / how do I do it?
4. WHAT should I prescribe?

Current management of Staphylococcus aureus

Prof. Steven Tong

In this lecture on management of S. aureus, Prof. Steven Tong (Doherty Institute, Royal Melbourne Hospital), presents on the following topics:

* Epidemiology
* Principles of care
* Current controversies
- Echocardiography
- Penicillin susceptible S. aureus (PSSA)
- Methicillin sensitive S. Aureus (MSSA)
- Oral switch
- PET/CT scans

Plenary 5: AMR control under One Health

Prof. Ramanan Laxminarayan

Global leader Prof. Ramanan Laxminarayan presents an excellent plenary lecture on understanding how antimicrobial resistance (AMR) should be managed in the One Health context.

Topics covered include:

* Drug resistance overview
* One Health concept
* Antimicrobials in food producing animals
* Antimicrobials in aquaculture
* Climate change and antibiotic resistance
* Global warming and fungal pathogens
* Interacting with the environment
* Using One Health framework to prevent resistance
* Surveillance networks
* Q&A with Prof. John Turnidge

Keynote 1: New therapeutic developments for fungal infections

Prof. Monica Slavin

In the lecture, Dr Slavin discusses the following:

1. Need for new antifungals
2. New treatment options in clinical trials: focus on rezafungin, brexafungerp, manogepix and olorofim
3. Update on azoles
4. Other advances
5. Conclusion and future directions

Plenary 4: HIV to COVID-19 & beyond: the role of antivirals in responding to pandemics

Prof. Sharon Lewin

Topics include direct acting antivirals for COVID-19, the delay in antiviral development for COVID-19, molecular technology platforms for antiviral development and the challenge of implementation.

Plenary 3: Phages – from personalised therapy to regulatory approval

Prof. Jon Iredell

Prof. Iredell presents strategies to develop novel phage therapy from regulatory approval to personalised therapy.

Plenary 2: Treatment of multidrug resistant Pseudomonas aeruginosa infections

Prof. Juan-Pablo Horcajada

Topics discussed include:

* Importance and frequency of MDR Pseudomonas aeruginosa infections
* High-risk clones. Mechanisms of resistance
* Treatment with colistin
* Hollow fiber model applied to P. aeruginosa infections
* Current antimicrobial options

Plenary 1: Microbial Theranostics - a Resistance Combatting Strategy

Prof. Robin Patel

In this lecture, Prof. Patel presents a potential strategy to help in the fight against the global antimicrobial resistance crisis through better diagnostics and better use of diagnostics.

Prof. Patel was awarded the Hamao Umezawa Memorial Award (HUMA) which is the highest award given by ISAC for outstanding contributions in the field of antimicrobial chemotherapy. The award is generously sponsored by the Microbial Chemistry Research Foundation of Japan.